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194
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BMCBI
2010
15 years 7 months ago
2010
Background: With advances in high-throughput genomics and proteomics, it is challenging for biologists to deal with large data files and to map their data to annotations in public...
201
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BMCBI
2010
2010
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
15 years 7 months ago
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
232
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BMCBI
2010
15 years 7 months ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
204
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BMCBI
2010
15 years 7 months ago
2010
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
197
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BMCBI
2010
15 years 7 months ago
2010
Background: Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and crit...