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BMCBI
2008
160views more  BMCBI 2008»
15 years 7 months ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
201
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 7 months ago
Efficiency clustering for low-density microarrays and its application to QPCR
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...
Eric F. Lock, Ryan Ziemiecki, J. S. Marron, Dirk P...
BMCBI
2007
95views more  BMCBI 2007»
15 years 7 months ago
ZPS: visualization of recent adaptive evolution of proteins
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
Sujay Chattopadhyay, Daniel E. Dykhuizen, Evgeni V...
BMCBI
2010
97views more  BMCBI 2010»
15 years 7 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
216
Voted
BMCBI
2007
99views more  BMCBI 2007»
15 years 7 months ago
Statistical significance of cis-regulatory modules
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
Dustin E. Schones, Andrew D. Smith, Michael Q. Zha...
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