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207
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BMCBI
2008
15 years 7 months ago
2008
Background: There has been a lot of interest in recent years focusing on the modeling and simulation of Gene Regulatory Networks (GRNs). However, the evolutionary mechanisms that ...
219
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BMCBI
2008
15 years 7 months ago
2008
Background: The amount of gene expression data in the public repositories, such as NCBI Gene Expression Omnibus (GEO) has grown exponentially, and provides a gold mine for bioinfo...
180
Voted
BMCBI
2007
15 years 7 months ago
2007
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
209
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BMCBI
2007
15 years 7 months ago
2007
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
211
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BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
15 years 7 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...