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BMCBI
2011
15 years 2 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
SIGMOD
2009
ACM
250views Database» more  SIGMOD 2009»
16 years 8 months ago
Query processing techniques for solid state drives
Solid state drives perform random reads more than 100x faster than traditional magnetic hard disks, while offering comparable sequential read and write bandwidth. Because of their...
Dimitris Tsirogiannis, Stavros Harizopoulos, Mehul...
SPAA
2009
ACM
16 years 8 months ago
Dynamic external hashing: the limit of buffering
Hash tables are one of the most fundamental data structures in computer science, in both theory and practice. They are especially useful in external memory, where their query perf...
Zhewei Wei, Ke Yi, Qin Zhang
BMCBI
2010
167views more  BMCBI 2010»
15 years 7 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BMCBI
2011
15 years 2 months ago
PileLine: a toolbox to handle genome position information in next-generation sequencing studies
Background: Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due to their huge size and the lack of approp...
Daniel Glez-Peña, Gonzalo Gómez-L&oa...
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