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BMCBI
2010
130views more  BMCBI 2010»
15 years 7 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BMCBI
2010
89views more  BMCBI 2010»
15 years 7 months ago
Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS)
Background: Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentratio...
Jennifer M. Staab, Thomas M. O'Connell, Shawn M. G...
BIOSYSTEMS
2008
129views more  BIOSYSTEMS 2008»
15 years 7 months ago
Reconstruction of DNA sequences using genetic algorithms and cellular automata: Towards mutation prediction?
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...
Ch. Mizas, Georgios Ch. Sirakoulis, Vasilios A. Ma...
BMCBI
2010
95views more  BMCBI 2010»
15 years 7 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BIOSYSTEMS
2007
107views more  BIOSYSTEMS 2007»
15 years 7 months ago
Calcium signalling in astrocytes and modulation of neural activity
Up to few years ago astrocytes have been considered as passive elements of brain, providing structural and metabolic support to the neurons, but playing little role in information...
Angelo Di Garbo, Michele Barbi, Santi Chillemi, Su...
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