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BMCBI
2005
84views more  BMCBI 2005»
15 years 6 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
BMCBI
2005
98views more  BMCBI 2005»
15 years 6 months ago
Iterative approach to model identification of biological networks
Background: Recent advances in molecular biology techniques provide an opportunity for developing detailed mathematical models of biological processes. An iterative scheme is intr...
Kapil G. Gadkar, Rudiyanto Gunawan, Francis J. Doy...
BMCBI
2005
201views more  BMCBI 2005»
15 years 6 months ago
A comparative study of discriminating human heart failure etiology using gene expression profiles
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
Xiaohong Huang, Wei Pan, Suzanne Grindle, Xinqiang...
BMCBI
2005
134views more  BMCBI 2005»
15 years 6 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
BMCBI
2005
163views more  BMCBI 2005»
15 years 6 months ago
Rank-invariant resampling based estimation of false discovery rate for analysis of small sample microarray data
Background: The evaluation of statistical significance has become a critical process in identifying differentially expressed genes in microarray studies. Classical p-value adjustm...
Nitin Jain, HyungJun Cho, Michael O'Connell, Jae K...
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