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BMCBI
2007
194views more  BMCBI 2007»
15 years 7 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
BMCBI
2010
133views more  BMCBI 2010»
15 years 7 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
ALGORITHMICA
2006
139views more  ALGORITHMICA 2006»
15 years 7 months ago
CONQUEST: A Coarse-Grained Algorithm for Constructing Summaries of Distributed Discrete Datasets
Abstract. In this paper we present a coarse-grained parallel algorithm, CONQUEST, for constructing boundederror summaries of high-dimensional binary attributed data in a distribute...
Jie Chi, Mehmet Koyutürk, Ananth Grama
BMCBI
2006
166views more  BMCBI 2006»
15 years 7 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
BMCBI
2006
121views more  BMCBI 2006»
15 years 7 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...