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245
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BMCBI
2010
15 years 7 months ago
2010
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
203
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BMCBI
2010
15 years 7 months ago
2010
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
235
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BMCBI
2010
15 years 7 months ago
2010
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
207
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BMCBI
2010
15 years 7 months ago
2010
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
197
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BMCBI
2010
15 years 7 months ago
2010
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...