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BMCBI
2010
161views more  BMCBI 2010»
15 years 7 months ago
CGHpower: exploring sample size calculations for chromosomal copy number experiments
Background: Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but ad...
Ilari Scheinin, Jose A. Ferreira, Sakari Knuutila,...
BMCBI
2010
102views more  BMCBI 2010»
15 years 7 months ago
Alignment and clustering of phylogenetic markers - implications for microbial diversity studies
Background: Molecular studies of microbial diversity have provided many insights into the bacterial communities inhabiting the human body and the environment. A common first step ...
James Robert White, Saket Navlakha, Niranjan Nagar...
BMCBI
2010
143views more  BMCBI 2010»
15 years 7 months ago
An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location inf
Background: Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout al...
Kaname Kojima, Masao Nagasaki, Satoru Miyano
BMCBI
2010
101views more  BMCBI 2010»
15 years 7 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
BMCBI
2010
77views more  BMCBI 2010»
15 years 7 months ago
web cellHTS2: A web-application for the analysis of high-throughput screening data
Background: The analysis of high-throughput screening data sets is an expanding field in bioinformatics. Highthroughput screens by RNAi generate large primary data sets which need...
Oliver Pelz, Moritz Gilsdorf, Michael Boutros
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