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IJCAI
1989
15 years 8 months ago
Functional Representation of Designs and Redesign Problem Solving
gn problem can be abstractly characterized as a constrained function-to-structure mapping. The de­ sign task takes as input the specifications of the desired functions of a device...
Ashok K. Goel, B. Chandrasekaran
BMCBI
2007
112views more  BMCBI 2007»
15 years 7 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
BMCBI
2007
147views more  BMCBI 2007»
15 years 7 months ago
Improved residue contact prediction using support vector machines and a large feature set
Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
Jianlin Cheng, Pierre Baldi
JCC
2008
88views more  JCC 2008»
15 years 7 months ago
A self-organizing algorithm for molecular alignment and pharmacophore development
Abstract: We present a method for simultaneous three-dimensional (3D) structure generation and pharmacophorebased alignment using a self-organizing algorithm called Stochastic Prox...
Deepak Bandyopadhyay, Dimitris K. Agrafiotis
BMCBI
2005
100views more  BMCBI 2005»
15 years 7 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...