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BMCBI
2010
190views more  BMCBI 2010»
15 years 7 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2008
134views more  BMCBI 2008»
15 years 7 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
SIGSOFT
2008
ACM
16 years 7 months ago
Predicting failures with developer networks and social network analysis
Software fails and fixing it is expensive. Research in failure prediction has been highly successful at modeling software failures. Few models, however, consider the key cause of ...
Andrew Meneely, Laurie Williams, Will Snipes, Jaso...
CIBCB
2007
IEEE
15 years 11 months ago
Prediction of Enzyme Catalytic Sites from Sequence Using Neural Networks
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Swati Pande, Amar Raheja, Dennis R. Livesay
BMCBI
2008
147views more  BMCBI 2008»
15 years 7 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...