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BMCBI
2007
116views more  BMCBI 2007»
15 years 7 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
ICDM
2007
IEEE
121views Data Mining» more  ICDM 2007»
16 years 1 months ago
Finding Predictive Runs with LAPS
We present an extension to the Lasso [9] for binary classification problems with ordered attributes. Inspired by the Fused Lasso [8] and the Group Lasso [10, 4] models, we aim to...
Suhrid Balakrishnan, David Madigan
BMCBI
2010
98views more  BMCBI 2010»
15 years 7 months ago
Learning to predict expression efficacy of vectors in recombinant protein production
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
Wen-Ching Chan, Po-Huang Liang, Yan-Ping Shih, Uen...
BMCBI
2007
121views more  BMCBI 2007»
15 years 7 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
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BMCBI
2010
108views more  BMCBI 2010»
15 years 7 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan