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BMCBI
2010
96views more  BMCBI 2010»
15 years 7 months ago
A statistical framework for differential network analysis from microarray data
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Ryan Gill, Somnath Datta, Susmita Datta
BMCBI
2008
124views more  BMCBI 2008»
15 years 7 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2008
105views more  BMCBI 2008»
15 years 7 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
BMCBI
2005
97views more  BMCBI 2005»
15 years 7 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
CCS
2011
ACM
14 years 7 months ago
SCRIPTGARD: automatic context-sensitive sanitization for large-scale legacy web applications
We empirically analyzed sanitizer use in a shipping web application with over 400,000 lines of code and over 23,244 methods, the largest empirical analysis of sanitizer use of whi...
Prateek Saxena, David Molnar, Benjamin Livshits