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» Testing with Functions as Specifications
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BMCBI
2007
131views more  BMCBI 2007»
15 years 7 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
IPM
2008
100views more  IPM 2008»
15 years 7 months ago
Query-level loss functions for information retrieval
Many machine learning technologies such as support vector machines, boosting, and neural networks have been applied to the ranking problem in information retrieval. However, since...
Tao Qin, Xu-Dong Zhang, Ming-Feng Tsai, De-Sheng W...
SODA
2008
ACM
110views Algorithms» more  SODA 2008»
15 years 8 months ago
Why simple hash functions work: exploiting the entropy in a data stream
Hashing is fundamental to many algorithms and data structures widely used in practice. For theoretical analysis of hashing, there have been two main approaches. First, one can ass...
Michael Mitzenmacher, Salil P. Vadhan
BMCBI
2007
144views more  BMCBI 2007»
15 years 7 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
BMCBI
2005
124views more  BMCBI 2005»
15 years 7 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...