Background: Traditional algorithms for hidden Markov model decoding seek to maximize either the probability of a state path or the number of positions of a sequence assigned to th...
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Background: Interest is growing in the application of syntactic parsers to natural language processing problems in biology, but assessing their performance is difficult because di...
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...