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210
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BMCBI
2010
118views more  BMCBI 2010»
15 years 7 months ago
Detecting lateral gene transfers by statistical reconciliation of phylogenetic forests
Background: To understand the evolutionary role of Lateral Gene Transfer (LGT), accurate methods are needed to identify transferred genes and infer their timing of acquisition. Ph...
Sophie S. Abby, Eric Tannier, Manolo Gouy, Vincent...
218
Voted
BMCBI
2010
161views more  BMCBI 2010»
15 years 7 months ago
FRASS: the web-server for RNA structural comparison
Background: The impressive increase of novel RNA structures, during the past few years, demands automated methods for structure comparison. While many algorithms handle only small...
Svetlana Kirillova, Silvio C. E. Tosatto, Oliviero...
207
Voted
BMCBI
2010
193views more  BMCBI 2010»
15 years 7 months ago
caGrid Workflow Toolkit: A Taverna based workflow tool for cancer Grid
Background: In biological and medical domain, the use of web services made the data and computation functionality accessible in a unified manner, which helped automate the data pi...
Wei Tan, Ravi K. Madduri, Aleksandra Nenadic, Stia...
227
Voted
BMCBI
2008
110views more  BMCBI 2008»
15 years 7 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
174
Voted
BMCBI
2010
136views more  BMCBI 2010»
15 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
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