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BMCBI
2006
143views more  BMCBI 2006»
15 years 7 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
111views more  BMCBI 2006»
15 years 7 months ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover
BMCBI
2006
200views more  BMCBI 2006»
15 years 7 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
BMCBI
2006
151views more  BMCBI 2006»
15 years 7 months ago
Machine learning and word sense disambiguation in the biomedical domain: design and evaluation issues
Background: Word sense disambiguation (WSD) is critical in the biomedical domain for improving the precision of natural language processing (NLP), text mining, and information ret...
Hua Xu, Marianthi Markatou, Rositsa Dimova, Hongfa...
BMCBI
2006
154views more  BMCBI 2006»
15 years 7 months ago
Analysis with respect to instrumental variables for the exploration of microarray data structures
Background: Evaluating the importance of the different sources of variations is essential in microarray data experiments. Complex experimental designs generally include various fa...
Florent Baty, Michaël Facompré, Jan Wi...