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BMCBI
2006
108views more  BMCBI 2006»
15 years 7 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
197
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BMCBI
2006
99views more  BMCBI 2006»
15 years 7 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2006
151views more  BMCBI 2006»
15 years 7 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman
190
Voted
BMCBI
2006
134views more  BMCBI 2006»
15 years 7 months ago
An approach for clustering gene expression data with error information
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
Brian Tjaden
206
Voted
BMCBI
2006
123views more  BMCBI 2006»
15 years 7 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger
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