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176
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BMCBI
2010
15 years 7 months ago
2010
Background: The budding yeast Saccharomyces cerevisiae is one of the most widely studied model organisms in aging-related science. Although several genetic modifiers of yeast long...
232
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BMCBI
2010
15 years 7 months ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
176
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BMCBI
2010
15 years 7 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
175
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BMCBI
2010
15 years 7 months ago
2010
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
221
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BMCBI
2010
2010
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
15 years 7 months ago
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...